Identification of srv , a PrfA-Like Regulator of Group A Streptococcus That Influences Virulence
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چکیده
منابع مشابه
Identification of srv, a PrfA-like regulator of group A streptococcus that influences virulence.
We have identified a Crp/Fnr-like transcriptional regulator of Streptococcus pyogenes that when inactivated attenuates virulence. The gene, named srv for streptococcal regulator of virulence, encodes a 240-amino-acid protein with 53% amino acid similarity to PrfA, a transcriptional activator of virulence in Listeria monocytogenes.
متن کاملA response regulator that represses transcription of several virulence operons in the group A streptococcus.
A search for homologs of the Bacillus subtilis PhoP response regulator in the group A streptococcus (GAS) genome revealed three good candidates. Inactivation of one of these, recently identified as csrR (J. C. Levin and M. R. Wessels, Mol. Microbiol. 30:209-219, 1998), caused the strain to produce mucoid colonies and to increase transcription of hasA, the first gene in the operon for capsule sy...
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Group A Streptococcus (GAS) possesses a complex regulatory system enabling the organism to colonize a range of physiologically distinct host sites. Within this network of regulators is the streptococcal regulator of virulence (Srv). Srv is a member of the CRP/FNR family of transcriptional regulators and is most similar to pleiotropic regulatory factor A (PrfA), a positive regulator of virulence...
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15 صفحه اولa decsription of persian deixis
the significance of the study of deixis was then mentioned. the purpose of the present study from the outset was to provide a comprehensive overview of all kinds of deixis in persian, describing and defining each in true while considering them structurally and semantically. chapter two consisted of two main parts. a review of the english studies in this respect, besides presenting persian liter...
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 2004
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.72.3.1799-1803.2004